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Automated Confocal Imaging and High-Content Screening for Cytomics
Book chapter

Automated Confocal Imaging and High-Content Screening for Cytomics

Maria A. DeBernardi, Stephen M. Hewitt and Andres Kriete
Handbook Of Biological Confocal Microscopy, pp 809-817
2006

Abstract

Agarose Plug Cell Microarray Confocal Imaging High Content Screening High Throughput Screening
The vast amount of biological information emerging from largescale high-volume genomics and proteomics has significantly changed biological research. The problem is, however, that we currently do not have the methods to analyze the enormous complexity of cells or cellular systems within reasonable time intervals using the traditional approach of hypothesis formulation followed by experimental verification. One challenge is that the data gained from observing a few cells is rarely suited for statistical evaluation. This limitation has stimulated development of new approaches to the comprehensive collection of information with more immediate biological importance at the cellular level (cytomics). This effort spans both basic biomedical research and drug development.

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